Seasonal flu may develop Parkinson"s disease

Researchers conducted study on critical neuropsychiatric symptoms during an influenza infection. Related to treatment with antiviral drugs Neuropsychiatric symptoms are more likely in connection with the influenza infection. And occur also in the absence of antiviral drug exposure.

Moreover, recent study reveals that Influenza which cause neurological consequence with previous infections. This associated with encephalitis lethargica known as sleepy sickness an entity displaying Parkinson’s disease (PD) signs and symptoms. Environmental factors, including infection with seasonal influenza, may increase the risk of developing Parkinson"s disease. A new study suggests most cases of Parkinson"s have no known cause. Researchers continue and study possible factors that may contribute to the disease.

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Growth of Parkinson"s in Mice

Certain strain of influenza virus condition in mice to develop pathologies are similar in Parkinson"s disease. Here we demonstrate that even mice who fully recover from the H1N1 “Swine flu” influenza virus. Responsible for the previous widespread are later more capable to chemical toxins known to cause Parkinson"s

In addition, that a deadly H5N1 strain of influenza "bird flu" has a high mortality rate of 60 percent. Those infected by died from the disease was able to infect nerve cells travel to the brain and cause inflammation. That would later result in Parkinson"s-like symptoms in mice. Inflammation in the brain don"t resolve appropriately after traumatic injury to head, has also linked to Parkinson"s. The researchers looked at a less harmful strain, the H1N1 "swine flu," that does not infect neurons, but which still caused inflammation in the brain via inflammatory chemicals or cytokines released by immune cells involved in fighting the infection.

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Using a model of Parkinson"s disease a toxin MPTP induces Parkinson"s-like symptoms in humans and mice. Infected mice with H1N1, even long after the initial infection had more severe Parkinson"s symptoms. Mice vaccinated against the H1N1 given antiviral medications such as Tamiflu. The time of flu infection increased sensitivity to MPTP is eliminated.