Study challenges the importance of compulsory water intake read more at here www.spinonews.com/index.php/item/1190-study-challenges-the-importance-of-compulsory-water-intake

A multi-institutional study led by Monash University has revealed the mechanism that regulates fluid intake in the human body and stops us from over-drinking, which can cause potentially fatal water intoxication.

The study showed that a swallowing inhibition is activated by the brain after excess liquid is consumed, helping maintain tightly calibrated volumes of water in the body.

Associate Professor Michael Farrell from the Monash Biomedicine Discovery Institute oversaw the work by University of Melbourne as part of a collaboration with several Melbourne institutes.

Building on a previous study, the researchers asked participants to rate the amount of effort required to swallow water under two conditions, following exercise when they were thirsty and later after they were persuaded to drink an excess amount of water.

Farrell said, the results showed a three-fold increase in effort after over-drinking. Here, for the first time we found effort-full swallowing after drinking excess water, which meant they were having to overcome some sort of resistance.

This was compatible with our notion that the swallowing reflex becomes inhibited once enough water has been drunk.

Farrell used functional magnetic resonance imaging (fMRI) to measure activity in various parts of the brain, focusing on the brief period just before swallowing.

The FMRI showed the right prefrontal areas of the brain were much more active when participants were trying to swallow with much effort, suggesting the frontal cortex steps in to override the swallowing inhibition so drinking could occur according to the researchers' instructions.

Cases when athletes in marathons were told to load up with water and died, in certain circumstances, because they slavishly followed these recommendations and drank far in excess of need.

Drinking too much water in the body puts it in danger of water intoxication or hyponatremia, when vital levels of sodium in the blood become abnormally low potentially causing symptoms ranging from lethargy and nausea to convulsions and coma.

Farrell said, elderly people, often didn't drink enough and should watch their intake of fluids.